D20 EME Safety, hygiene, quality assurance - VEGA Instruments meet the measurement needs of the pharmaceutical industry

The biotechnology and pharmaceutical industries place many requirements on the reliability of measuring instruments: safety, flexibility, meeting stringent hygiene standards such as FDA, ISPE GAMP, ASME-BPE or EHED, just to name a few of the many requirements that instruments must meet. From pre-treatment, fermentation, and separation to warehousing, precise dosing, filling, and regular cleaning during operation, measuring instruments simplify the pharmaceutical production process and help the pharmaceutical industry improve quality and efficiency.

VEGA offers a full range of level and pressure measurement solutions for the pharmaceutical industry, with instruments that offer the following benefits:

Standard process connection
Unified health adaptation system
Seal against penetration
Strong and durable
Designed for CIP and SIP processes
So, which measurement tasks can VEGA meters solve and which applications can they be used in?

VEGA gauges are designed for the harsh conditions of CIP and SIP processes: even during process operation and at temperatures up to 150°C, the gauges ensure adequate storage of all required media.

01

Liquid level measurement

🟡 VEGAPULS 42 radar level gauge

The radar level gauge VEGAPULS 42 is particularly suitable for applications where levels change rapidly in fully automated production.

In order to meet the strict sanitary requirements of the process, the liquid level meter can be equipped with a variety of sanitary adapter adapters. With IO-Link technology, VEGAPULS 42 can quickly transfer process data to the user's commercial or experimental system. The meter uses non-contact 80GHz radar technology to measure and operate without maintenance.

With a measuring distance of up to 15m and a temperature range of up to 150°C, VEGAPULS 42 can be used in metering systems and downstream process steps such as conveying systems and filling systems.

🟡 VEGAPULS 6X radar level gauge

For more challenging applications, the highly accurate radar level gauge VEGAPULS 6X is the ideal solution. The radar waves of VEGAPULS 6X have a strong focusing ability, and internal components such as stirring devices do not affect their reliable measurement results. With a larger signal dynamic range, the meter can also always accurately measure oily media and other media with poor reflective properties.



VEGA level gauges use standard connectors such as M12 and solenoid plugs for quick and easy integration into facility systems.

02

Pressure measurement

🟡 VEGABAR 28 pressure transmitter

For feeding tubes for heating media, it is critical that the instrument responds quickly. In such applications, the VEGABAR 28 pressure transmitter enables safe and reliable monitoring of gases, vapors and liquids at temperatures up to 130°C. The capacitive ceramic CERTEC® measuring element used in the meter is developed and produced by VEGA itself. It has the advantages of abrasion resistance, no filling oil, long-term measurement stability, and high overload resistance. The VEGABAR 28 provides a common interface for sanitary adapters, thereby reducing the user's installation effort and spare parts inventory.

03

Limit measurement

🟡 VEGAPOINT 31 Capacitor limit switch

The VEGAPOINT 31 capacitive limit switch is easy to operate and equipped with 360° color light ring status display, making the measurement process clear at a glance. The limit detection is not affected by the medium, and the function is reliable. In addition, VEGAPOINT 31 is small and suitable for tight Spaces.

🟡 VEGASWING 61 Vibration limit switch

The vibration limit switch VEGASWING 61 is reliable and durable for high or low alarm at measuring points such as cleaning liquid storage tanks. It is suitable for all kinds of liquids, is not affected by the installation position, and can reliably measure the media limit with millimeter accuracy. VEGA offers the right solution for every application.

Related application

In CIP cleaning fluid tanks

Measure liquid level and limit

The cleaning of process technology equipment used in the pharmaceutical industry is carried out within the framework of a proven "Clean in place (CIP)" process, which ensures that production containers are kept sterile. Here, a sodium hydroxide solution or concentrated acid is usually used as a cleaning agent, which is stored in the storage tank of the on-site cleaning equipment and diluted in the production container. The storage of cleaning agents can be optimized through liquid level measurement. Overflow and dry operation can be reliably prevented by measuring limits. Measure the material level and limit in the capsule filling machine

Empty raw material capsules and pharmaceutical active ingredient particles are generally stored above the filling machine. To ensure a continuous supply of raw materials, it is necessary to measure material levels reliably. The raw capsules are only lightly glued together and can be easily separated by vacuum, allowing the upper part to separate from the lower part. The pellets are then poured into the lower part of the capsule. The finished capsule filled with the drug is then transported through a hose system to a collection container. It is necessary to measure the limit here to prevent overflow.

In the production of enzymes, proteins and antibodies

Perform level measurement and pressure measurement

Drugs often require cells or microbes, which are grown in bioreactors. The highest hygiene requirements need to be met and the containers must be optimally cleaned. Because even the slightest contamination with other organic matter can cause the wrong reaction to occur. Most of the processes referred to here are so-called flow-add culture processes, in which the reactor is completely filled at one time and emptied again after a reaction or growth period. To obtain a high-value end product, the pressure and level in the reactor must be continuously monitored throughout the process.